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IL4R MaxPab mouse polyclonal antibody (B01)   MaxPab

  • カタログ番号 # : H00003566-B01
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  • サイズ
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  • 50 uL
  • JPY ¥ 40,000
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    1. この価格は、 Japanでのみ有効です。国を選択して下さい。
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human IL4R protein.
  • Immunogen:
  • IL4R (NP_001008699, 1 a.a. ~ 227 a.a) full-length human protein.
  • Sequence:
  • MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSNIC
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Flow Cytometry
  • Flow Cytometryenlargeenlarge this image
  • FACS analysis of negative control 293 cells (Black) and IL4R expressing 293 cells (Green) using IL4R purified MaxPab mouse polyclonal antibody.
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of IL4R expression in transfected 293T cell line (H00003566-T01) by IL4R MaxPab polyclonal antibody.

    Lane 1: IL4R transfected lysate(24.97 KDa).
    Lane 2: Non-transfected lysate.
  • Protocol Download
  • Detection Antibody
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Detection Antibody
  • Gene Information
  • Entrez GeneID:
  • 3566
  • Gene Name:
  • IL4R
  • Gene Alias:
  • CD124,IL4RA
  • Gene Description:
  • interleukin 4 receptor
  • Gene Summary:
  • This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000122506,interleukin 4 receptor alpha chain,interleukin-4 receptor alpha chain
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