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- Home > Products > siRNA/Chimera > Pre-design Chimera > Membrane > Transporter > FXN Pre-design Chimera RNAi
FXN Pre-design Chimera RNAi
- カタログ番号 # : H00002395-R05
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 10 nmol
- ..........
- 20 nmol
- ..........
-
- This product is not available in Japan.
- お問い合わせ
-
Contact Information
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166
- Specification
- Product Description:
- Homo sapiens frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_000144
- Target Region:
- 3' Untranslated Region (3'UTR)
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 2395
- Gene Name:
- FXN
- Gene Alias:
- CyaY,FA,FARR,FRDA,MGC57199,X25
- Gene Description:
- frataxin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- OTTHUMP00000021428
- Related Disease
- Cardiomegaly
- Cardiomyopathies
- Cardiovascular Diseases
- Cerebellar Ataxia
- Chronic Disease
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fragile X Syndrome
- Fragile X syndrome
- Friedreich Ataxia
- Friedreich's ataxia
- Genetic Predisposition to Disease
- Glucose Intolerance
- Interview, Psychological
- Muscular Atrophy, Spinal
- Myocardial Infarction
- Myotonic Dystrophy
- Myotonic dystrophy
