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- Home > Products > Polyclonal Ab > Human > Signal Transduction > DSCR1 polyclonal antibody (A02)
DSCR1 polyclonal antibody (A02)
- カタログ番号 # : H00001827-A02
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 50 uL
- JPY ¥ 28,000
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- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length recombinant DSCR1.
- Immunogen:
- DSCR1 (AAH02864, 1 a.a. ~ 197 a.a) full-length recombinant protein with GST tag.
- Sequence:
- MEEVDLRDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTQIHLS
- Host:
- Mouse
- Reactivity:
- Human
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Application Image
- ELISA
- Entrez GeneID:
- 1827
- GeneBank Accession#:
- BC002864
- Protein Accession#:
- AAH02864
- Gene Name:
- RCAN1
- Gene Alias:
- ADAPT78,CSP1,DSC1,DSCR1,MCIP1,RCN1
- Gene Description:
- regulator of calcineurin 1
- Omim ID:
- 602917
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- Down syndrome candidate region 1,Down syndrome critical region gene 1,calcipressin 1,calcium and oxidant-inducible mRNA,modulatory calcineurin-interacting protein 1,myocyte-enriched calcineurin-interacting protein 1,near DSCR proline-rich protein
- Related Disease
