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- Home > Products > siRNA/Chimera > Pre-design Chimera > Plasma/Serum > SERPINA3 Pre-design Chimera RNAi
SERPINA3 Pre-design Chimera RNAi
- カタログ番号 # : H00000012-R01
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 10 nmol
- ..........
- 20 nmol
- ..........
-
- This product is not available in Japan.
- お問い合わせ
-
Contact Information
Email : sales@abnova.com
Phone : +886-2-87511888
Fax : +886-2-87511166
- Specification
- Product Description:
- Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3), mRNA.
- Reactivity:
- Human
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001085
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 12
- Gene Name:
- SERPINA3
- Gene Alias:
- AACT,ACT,GIG24,GIG25,MGC88254
- Gene Description:
- serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
- Omim ID:
- 107280
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq
- Other Designations:
- alpha-1-antichymotrypsin,antichymotrypsin,growth-inhibiting protein 24,growth-inhibiting protein 25,serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3,serine (or cysteine) proteinase inhibitor, clade A, memb
- Related Disease
- Acute Disease
- alpha 1-Antitrypsin Deficiency
- Alpha-1-antitrypsin deficiency
- Alzheimer Disease
- Alzheimer disease
- Aneurysm, Ruptured
- Asthma
- Asthma
- Brain Ischemia
- Bronchial Hyperreactivity
- Cardiovascular Diseases
- Cerebral Amyloid Angiopathy
- Cerebral Hemorrhage
- Cerebrovascular Accident
- Chronic Disease
- Cognition
- Cognition Disorders
- Cystic fibrosis
- Dementia
