Immunoperoxidase of monoclonal antibody to SERPINA3 on formalin-fixed paraffin-embedded human ovary, clear cell carcinoma. [antibody concentration 1 ug/ml]
Immunoprecipitation of SERPINA3 transfected lysate using anti-SERPINA3 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SERPINA3 MaxPab rabbit polyclonal antibody.
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq
Other Designations:
alpha-1-antichymotrypsin,antichymotrypsin,growth-inhibiting protein 24,growth-inhibiting protein 25,serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3,serine (or cysteine) proteinase inhibitor, clade A, memb