Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
Quality Control Testing:
Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
Supplied Product:
DAPI Counterstain (1500 ng/mL ) 250 uL
Storage Instruction:
Store at 4°C in the dark.
Note:
Hybridization position of the probes on the chromosome.
Probe 1: Size: Fluorophore: Location:
TFE3(Texas Red) Approximately 570kb Texas Red Xp11.22
Probe 2: Size: Fluorophore: Location:
TFE3(FITC) Approximately 550kb FITC Xp11.22
Probe Gap:
The gap between two probes is approximately 90 kb.
Origin:
Human
Source:
Genomic DNA
Notice:
We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991 [PubMed 1685140]).[supplied by OMIM
Other Designations:
OTTHUMP00000024272,Renal cell carcinoma, papillary,Transcription factor for IgH enhancer,transcription factor E family, member A,transcription factor E3