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- Home > Products > Polyclonal Ab > Phospho-Specific > DNMT1 (phospho S714) polyclonal antibody
DNMT1 (phospho S714) polyclonal antibody
- カタログ番号 # : PAB1660
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 41,000
- order now, ship next day
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of DNMT1.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S714 of human DNMT1.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation.
Leu YW, Rahmatpanah F, Shi H, Wei SH, Liu JC, Yan PS, Huang TH.Cancer Res. 2003 Oct 1;63(19):6110-5.
- 2.
- p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding.
Peterson EJ, Bogler O, Taylor SM.Cancer Res. 2003 Oct 15;63(20):6579-82.
- 3.
- Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.
Saito Y, Kanai Y, Nakagawa T, Sakamoto M, Saito H, Ishii H, Hirohashi S.Int J Cancer. 2003 Jul 1;105(4):527-32.
- Entrez GeneID:
- 1786
- Protein Accession#:
- NP_001370;P26358
- Gene Name:
- DNMT1
- Gene Alias:
- AIM,CXXC9,DNMT,FLJ16293,MCMT,MGC104992
- Gene Description:
- DNA (cytosine-5-)-methyltransferase 1
- Omim ID:
- 126375
- Gene Ontology:
- Hyperlink
- Gene Summary:
- DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CXXC finger protein 9,DNA methyltransferase 1
- Gene Pathway
- Related Disease
