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- Home > Products > MaxPab® Ab > Human > Binding > Others > MME MaxPab mouse polyclonal antibody (B01)
MME MaxPab mouse polyclonal antibody (B01) 
- カタログ番号 # : H00004311-B01
- 頻繁に訪問する :
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- 価格
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- 50 uL
- JPY ¥ 40,000
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- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human MME protein.
- Immunogen:
- MME (AAI01659.1, 1 a.a. ~ 750 a.a) full-length human protein.
- Sequence:
- MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
- Host:
- Mouse
- Reactivity:
- Human
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Note:
- For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- MME MaxPab polyclonal antibody. Western Blot analysis of MME expression in human kidney.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of MME expression in transfected 293T cell line (H00004311-T01) by MME MaxPab polyclonal antibody.
Lane 1: MME transfected lysate(82.5 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 4311
- GeneBank Accession#:
- NM_007287.1
- Protein Accession#:
- AAI01659.1
- Gene Name:
- MME
- Gene Alias:
- CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP
- Gene Description:
- membrane metallo-endopeptidase
- Omim ID:
- 120520
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq
- Other Designations:
- atriopeptidase,common acute lymphocytic leukemia antigen,enkephalinase,membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase),membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10),membrane metallo-endopeptidase
