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- Home > Products > MaxPab® Ab > Human > Binding > Others > ANK1 purified MaxPab rabbit polyclonal antibody (D01P)
ANK1 purified MaxPab rabbit polyclonal antibody (D01P) 
- カタログ番号 # : H00000286-D01P
- 頻繁に訪問する :
- サイズ
- 価格
- 在庫あ
- 入手可能
- カート
- 100 ug
- JPY ¥ 44,000
- order now, ship next day
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- この価格は、 Japanでのみ有効です。国を選択して下さい。
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Phone : +886-2-87511888
Fax : +886-2-87511166- 製品は、お客様に直接出荷されます。
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human ANK1 protein.
- Immunogen:
- ANK1 (AAH30957.1, 1 a.a. ~ 155 a.a) full-length human protein.
- Sequence:
- MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEDLSDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEVELRGSGLQPDLIEGRKGAQIVKRASLKRGKQ
- Host:
- Rabbit
- Reactivity:
- Human
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of ANK1 expression in transfected 293T cell line (H00000286-T01) by ANK1 MaxPab polyclonal antibody.
Lane 1: ANK1 transfected lysate(17.70 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 286
- GeneBank Accession#:
- BC030957.1
- Protein Accession#:
- AAH30957.1
- Gene Name:
- ANK1
- Gene Alias:
- ANK,SPH1,SPH2
- Gene Description:
- ankyrin 1, erythrocytic
- Omim ID:
- 182900
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified. [provided by RefSeq
- Other Designations:
- ankyrin 1,ankyrin-1, erythrocytic,ankyrin-R
