MRAS recombinant monoclonal antibody, clone 17H12
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MRAS.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human MRAS.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry(1:50-1:200)
Immunofluorescence(1:20-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of MRAS recombinant monoclonal antibody, clone 17H12 diluted at 1:600 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system.Immunofluorescence
Immunofluorescence staining of Hela Cells with MRAS recombinant monoclonal antibody, clone 17H12 at 1:200, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MRAS
Entrez GeneID
22808Protein Accession#
O14807Gene Name
MRAS
Gene Alias
FLJ42964, M-RAs, R-RAS3, RRAS3
Gene Description
muscle RAS oncogene homolog
Omim ID
608435Gene Ontology
HyperlinkGene Summary
Members of the RAS superfamily of GTP-binding proteins, which includes MRAS, are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors.[supplied by OMIM
Other Designations
muscle and microspikes RAS
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Interactome
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Pathway
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Disease
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