NPR2 recombinant monoclonal antibody, clone 19C7
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: HepG2 whole cell lysate; Lane 2: MCF-7 whole cell lysate.
Immunofluorescence
Immunofluorescence staining of Hela Cells with NPR2 recombinant monoclonal antibody, clone 19C7 at 1:25, counter-stained with DAPI.
Flow Cytometry
Overlay Peak curve showing Hela cells stained with NPR2 recombinant monoclonal antibody, clone 19C7 (red line) at 1:50.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human NPR2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human NPR2.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunofluorescence(1:20-1:200)
Western Blot(1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: HepG2 whole cell lysate; Lane 2: MCF-7 whole cell lysate.Immunofluorescence
Immunofluorescence staining of Hela Cells with NPR2 recombinant monoclonal antibody, clone 19C7 at 1:25, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing Hela cells stained with NPR2 recombinant monoclonal antibody, clone 19C7 (red line) at 1:50. -
Gene Info — NPR2
Entrez GeneID
4882Protein Accession#
P20594Gene Name
NPR2
Gene Alias
AMDM, ANPRB, GUC2B, GUCY2B, NPRB, NPRBi
Gene Description
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
Gene Ontology
HyperlinkGene Summary
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq
Other Designations
OTTHUMP00000021345|OTTHUMP00000045390|atrial natriuretic peptide B-type receptor|guanylate cyclase B|natriuretic peptide receptor B
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Interactome
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Pathway
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Disease
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