FLT1 recombinant monoclonal antibody, clone 40H4
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: JK whole cell lysate; Lane 2: Mouse Brain tissue lysate.
Immunohistochemistry
Immunohistochemistry image of FLT1 recombinant monoclonal antibody, clone 40H4 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system.
Flow Cytometry
Overlay Peak curve showing MCF-7 cells stained with FLT1 recombinant monoclonal antibody, clone 40H4 (red line) at 1:50.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human and mouse FLT1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human FLT1.
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunohistochemistry(1:50-1:200)
Western Blot(1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: JK whole cell lysate; Lane 2: Mouse Brain tissue lysate.Immunohistochemistry
Immunohistochemistry image of FLT1 recombinant monoclonal antibody, clone 40H4 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing MCF-7 cells stained with FLT1 recombinant monoclonal antibody, clone 40H4 (red line) at 1:50. -
Gene Info — FLT1
Entrez GeneID
2321Protein Accession#
P17948Gene Name
FLT1
Gene Alias
FLT, VEGFR1
Gene Description
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
Omim ID
165070Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia
Other Designations
fms-related tyrosine kinase 1|soluble VEGF receptor 1-14|soluble VEGFR1 variant 2|soluble VEGFR1 variant 21|vascular endothelial growth factor/vascular permeability factor receptor
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Interactome
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Pathway
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Disease
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