CAPN2 recombinant monoclonal antibody, clone 17E9
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CAPN2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human CAPN2.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Western Blot(1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: U87 whole cell lysate; Lane 2: U251 whole cell lysate; Lane3: PC3 whole cell lysate; Lane 4: A549 whole cell lysate; Lane 5: Hela whole cell lysate; Lane 6: HepG2 whole cell lysate; Lane 7: MCF-7 whole cell lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CAPN2
Entrez GeneID
824Protein Accession#
P17655Gene Name
CAPN2
Gene Alias
CANP2, CANPL2, CANPml, FLJ39928, mCANP
Gene Description
calpain 2, (m/II) large subunit
Omim ID
114230Gene Ontology
HyperlinkGene Summary
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
M-calpain|OTTHUMP00000035497|calcium-activated neutral proteinase|calpain 2, large [catalytic] subunit|calpain 2, large subunit|calpain M-type|calpain, large polypeptide L2|millimolar-calpain
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Interactome
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Disease
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