CCR8 recombinant monoclonal antibody, clone 4A19
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Flow Cytometry
Flow cytometry analysis of untransfected CHO-K1 cells (green line) and transfected human CCR8 CHO-K1 stable cells (red line) stained with CCR8 recombinant monoclonal antibody, clone 4A19 (Cat # RAB07553)(2ug/1*106cells). The cells were washed and then followed by FITC-conjugated anti-Human IgG Fc antibody.
The ELISA results show that the binding activity of CCR8 with CCR8 recombinant monoclonal antibody, clone 4A19 (Cat # RAB07553). Immobilized human CCR8 (CSB-MP004847HU) at 5 ug/mL can bind CCR8 recombinant monoclonal antibody, clone 4A19 (Cat # RAB07553), the EC50 is 11.20-15.63 ng/mL.
-
Specification
Product Description
Human recombinant monoclonal antibody raised against human CCR8.
Antibody Species
Human
Immunogen
Original antibody is raised against recombinant protein of human CCR8.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG1
Quality Control Testing
Binding activity
The ELISA results show that the binding activity of CCR8 with CCR8 recombinant monoclonal antibody, clone 4A19 (Cat # RAB07553). Immobilized human CCR8 (CSB-MP004847HU) at 5 ug/mL can bind CCR8 recombinant monoclonal antibody, clone 4A19 (Cat # RAB07553), the EC50 is 11.20-15.63 ng/mL.
Recommend Usage
ELISA
Flow Cytometry(1:20-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (0.03% Proclin 300 and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Flow cytometry analysis of untransfected CHO-K1 cells (green line) and transfected human CCR8 CHO-K1 stable cells (red line) stained with CCR8 recombinant monoclonal antibody, clone 4A19 (Cat # RAB07553)(2ug/1*106cells). The cells were washed and then followed by FITC-conjugated anti-Human IgG Fc antibody. -
Gene Info — CCR8
Entrez GeneID
1237Protein Accession#
P51685Gene Name
CCR8
Gene Alias
CDw198, CKR-L1, CKRL1, CMKBR8, CMKBRL2, CY6, GPR-CY6, MGC129966, MGC129973, TER1
Gene Description
chemokine (C-C motif) receptor 8
Omim ID
601834Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq
Other Designations
CC chemokine receptor 8|CC-chemokine receptor chemr1|chemokine (C-C) receptor 8|chemokine (C-C) receptor-like 2
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com