PTH1R recombinant monoclonal antibody, clone 1G7
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PTH1R.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human PTH1R.
Theoretical MW (kDa)
Calculated MW: 67
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of U-251 whole cell lysate, THP-1 whole cell lysate, Ntera-2 whole cell lysate with PTH1R recombinant monoclonal antibody, clone 1G7 (Cat # RAB07420).Enzyme-linked Immunoabsorbent Assay
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Gene Info — PTH1R
Entrez GeneID
5745Protein Accession#
Q03431Gene Name
PTH1R
Gene Alias
MGC138426, MGC138452, PTHR, PTHR1
Gene Description
parathyroid hormone 1 receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. [provided by RefSeq
Other Designations
PTH/PTHr receptor|PTH/PTHrP type I receptor|parathyroid hormone receptor 1|parathyroid hormone/parathyroid hormone-related peptide receptor|parathyroid hormone/parathyroid hormone-related protein receptor|seven transmembrane helix receptor
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Interactome
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Pathway
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Disease
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