TLR5 recombinant monoclonal antibody, clone 10D8
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of THP-1 whole cell lysate, RAW264.7 whole cell lysate, U-251 whole cell lysate, K562 whole cell lysate with TLR5 recombinant monoclonal antibody, clone 10D8 (Cat # RAB07409).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TLR5.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human TLR5.
Theoretical MW (kDa)
98
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of THP-1 whole cell lysate, RAW264.7 whole cell lysate, U-251 whole cell lysate, K562 whole cell lysate with TLR5 recombinant monoclonal antibody, clone 10D8 (Cat # RAB07409).Enzyme-linked Immunoabsorbent Assay
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Gene Info — TLR5
Entrez GeneID
7100Protein Accession#
O60602Gene Name
TLR5
Gene Alias
FLJ10052, MGC126430, MGC126431, SLEB1, TIL3
Gene Description
toll-like receptor 5
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq
Other Designations
OTTHUMP00000036039|Toll/interleukin-1 receptor-like protein 3
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Interactome
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Disease
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