SLC1A3 recombinant monoclonal antibody, clone R05-5D9
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SLC1A3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human SLC1A3.
Theoretical MW (kDa)
Calculated MW: 60 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end use.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol and 0.02% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
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Gene Info — SLC1A3
Entrez GeneID
6507Gene Name
SLC1A3
Gene Alias
EA6, EAAT1, FLJ25094, GLAST, GLAST1
Gene Description
solute carrier family 1 (glial high affinity glutamate transporter), member 3
Omim ID
600111Gene Ontology
HyperlinkGene Summary
Glutamate and aspartate are excitatory neurotransmitters that have been implicated in a number of pathologic states of the nervous system. Accumulation of extracellular excitatory amino acids can be cytotoxic and may also lower the seizure threshold in epilepsy. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system (Kirschner et al., 1994 [PubMed 8001975]).[supplied by OMIM
Other Designations
glutamate transporter variant EAAT1ex9skip
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Interactome
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Disease
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