ATG4B recombinant monoclonal antibody, clone R07-8A3
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human, mouse and rat ATG4B.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against protein corresponding to full length human ATG4B.
Theoretical MW (kDa)
Calculated MW: 44 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end use.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Flow Cytometry
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Gene Info — ATG4B
Entrez GeneID
23192Protein Accession#
Q9Y4P1Gene Name
ATG4B
Gene Alias
APG4B, AUTL1, MGC1353
Gene Description
ATG4 autophagy related 4 homolog B (S. cerevisiae)
Omim ID
611338Gene Ontology
HyperlinkGene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
APG4 autophagy 4 homolog B|autophagin-1
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