F2 recombinant monoclonal antibody, clone R01-9B6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human F2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against protein corresponding to full length human F2.
Theoretical MW (kDa)
Calculated MW: 70 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end use.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
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Gene Info — F2
Entrez GeneID
2147Protein Accession#
Q14209Gene Name
F2
Gene Alias
PT
Gene Description
coagulation factor II (thrombin)
Omim ID
176930Gene Ontology
HyperlinkGene Summary
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq
Other Designations
coagulation factor II|prothrombin B-chain|serine protease
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Interactome
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Disease
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