ATG4A recombinant monoclonal antibody, clone R05-3H3
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human ATG4A.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human ATG4A.
Theoretical MW (kDa)
Calculated MW: 45 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunohistochemistry (1/50-1/100)
Immunoprecipitation (1/20)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, 150mM NaCl, pH 7.4 (40% glycerol, 0.05% BSA and 0.01% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — ATG4A
Entrez GeneID
115201Protein Accession#
Q8WYN0Gene Name
ATG4A
Gene Alias
APG4A, AUTL2
Gene Description
ATG4 autophagy related 4 homolog A (S. cerevisiae)
Omim ID
300663Gene Ontology
HyperlinkGene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified. [provided by RefSeq
Other Designations
APG4 autophagy 4 homolog A|AUT-like 2, cysteine endopeptidase|OTTHUMP00000023822|OTTHUMP00000062893|autophagin 2|autophagy-related cysteine endopeptidase 2
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Interactome
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