CNR1 (phospho Ser316) recombinant monoclonal antibody, clone R05-9A1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CNR1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic phosphopeptide corresponding to residues surrounding Ser316 of human CNR1.
Theoretical MW (kDa)
Calculated MW: 53 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, 150mM NaCl, pH 7.4 (40% glycerol, 0.05% BSA and 0.01% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — CNR1
Entrez GeneID
1268Protein Accession#
P21554Gene Name
CNR1
Gene Alias
CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR
Gene Description
cannabinoid receptor 1 (brain)
Omim ID
114610Gene Ontology
HyperlinkGene Summary
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016838|OTTHUMP00000016839|OTTHUMP00000016840|central cannabinoid receptor
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