PON2 recombinant monoclonal antibody, clone R03-4U5
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PON2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human PON2
Theoretical MW (kDa)
Calculated MW: 39 kD
Reactivity
Human
Form
Liquid
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1/50-1/100)
Immunoprecipitation (1/20)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150mM NaCl, pH 7.4 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — PON2
Entrez GeneID
5445Gene Name
PON2
Gene Alias
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Gene Description
paraoxonase 2
Omim ID
602447Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
A-esterase 2|aromatic esterase 2|paraoxonase nirs|serum aryldialkylphosphatase 2|serum paraoxonase/arylesterase 2
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Interactome
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