PRKCQ recombinant monoclonal antibody, clone R05-5I4
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: U2OS whole cell lysate and Lane 2: C6 whole cell lysate with PRKCQ recombinant monoclonal antibody, clone R05-5I4 (Cat # RAB04470).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PRKCQ.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human PRKCQ.
Theoretical MW (kDa)
Calculated MW: 82 kD
Reactivity
Human, Rat
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, 150mM NaCl, pH 7.4 (40% glycerol, 0.05% BSA and 0.01% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: U2OS whole cell lysate and Lane 2: C6 whole cell lysate with PRKCQ recombinant monoclonal antibody, clone R05-5I4 (Cat # RAB04470). -
Gene Info — PRKCQ
Entrez GeneID
5588Protein Accession#
Q04759Gene Name
PRKCQ
Gene Alias
MGC126514, MGC141919, PRKCT, nPKC-theta
Gene Description
protein kinase C, theta
Omim ID
600448Gene Ontology
HyperlinkGene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq
Other Designations
OTTHUMP00000019053|OTTHUMP00000043364|OTTHUMP00000043365
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