CRADD recombinant monoclonal antibody, clone R02-1B3
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: HeLa whole cell lysate, Lane 2: A549 whole cell lysate, Lane 3: MCF-7 whole cell lysate and Lane 4: 293T whole cell lysate with CRADD recombinant monoclonal antibody, clone R02-1B3 (Cat # RAB04456).
Immunocytochemistry
Immunocytochemistry staining of HeLa cells with CRADD recombinant monoclonal antibody, clone R02-1B3 (Cat # RAB04456) (green). DAPI was stained the cell nucleus (blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CRADD.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human CRADD.
Theoretical MW (kDa)
Calculated MW: 23 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence (1:50-1:200)
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, 150mM NaCl, pH 7.4 (40% glycerol, 0.05% BSA and 0.01% Sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: HeLa whole cell lysate, Lane 2: A549 whole cell lysate, Lane 3: MCF-7 whole cell lysate and Lane 4: 293T whole cell lysate with CRADD recombinant monoclonal antibody, clone R02-1B3 (Cat # RAB04456).Immunocytochemistry
Immunocytochemistry staining of HeLa cells with CRADD recombinant monoclonal antibody, clone R02-1B3 (Cat # RAB04456) (green). DAPI was stained the cell nucleus (blue).Immunofluorescence
Immunoprecipitation
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Gene Info — CRADD
Entrez GeneID
8738Protein Accession#
P78560Gene Name
CRADD
Gene Alias
MGC9163, RAIDD
Gene Description
CASP2 and RIPK1 domain containing adaptor with death domain
Omim ID
603454Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq
Other Designations
RIP-associated ICH1/CED3-homologous protein with death domain|RIP-associated protein with a death domain|caspase and RIP adaptor with death domain|death adaptor molecule RAIDD|death domain containing protein CRADD
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Interactome
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Disease
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