TFPI recombinant monoclonal antibody, clone R08-6B8
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: A549 whole cell lysate and Lane 2: MCF-7 whole cell lysate with TFPI recombinant monoclonal antibody, clone R08-6B8 (Cat # RAB04432).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TFPI.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human TFPI.
Theoretical MW (kDa)
Calculated MW: 35 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: A549 whole cell lysate and Lane 2: MCF-7 whole cell lysate with TFPI recombinant monoclonal antibody, clone R08-6B8 (Cat # RAB04432). -
Gene Info — TFPI
Entrez GeneID
7035Protein Accession#
P10646Gene Name
TFPI
Gene Alias
EPI, LACI, TFI, TFPI1
Gene Description
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Omim ID
152310Gene Ontology
HyperlinkGene Summary
This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq
Other Designations
OTTHUMP00000163472|anti-convertin|extrinsic pathway inhibitor|lipoprotein-associated coagulation inhibitor|tissue factor pathway inhibitor
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Interactome
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Pathway
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Disease
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