XRCC1 recombinant monoclonal antibody, clone R02-0B0
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More Files
- More Functions
Western Blot
Western blot analysis of PC-12 whole cell lysate with XRCC1 recombinant monoclonal antibody, clone R02-0B0 (Cat # RAB04418).
Western Blot
Western blot analysis of Lane 1: A549 whole cell lysate, Lane 2: MCF-7 whole cell lysate and Lane 3: 293T whole cell lysate with XRCC1 recombinant monoclonal antibody, clone R02-0B0 (Cat # RAB04418).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human XRCC1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human XRCC1.
Theoretical MW (kDa)
Calculated MW: 69 kD
Reactivity
Human, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence (1:50-1:200)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of PC-12 whole cell lysate with XRCC1 recombinant monoclonal antibody, clone R02-0B0 (Cat # RAB04418).Western Blot
Western blot analysis of Lane 1: A549 whole cell lysate, Lane 2: MCF-7 whole cell lysate and Lane 3: 293T whole cell lysate with XRCC1 recombinant monoclonal antibody, clone R02-0B0 (Cat # RAB04418).Immunocytochemistry
Immunofluorescence
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Gene Info — XRCC1
Entrez GeneID
7515Protein Accession#
P18887Gene Name
XRCC1
Gene Alias
RCC
Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 1
Omim ID
194360Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq
Other Designations
DNA repair protein XRCC1|X-ray repair cross complementing protein 1|X-ray-repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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