Histone H2A (hydroxyl Y39) recombinant monoclonal antibody, clone R04-5I3
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human histone H2A.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic hydroxyl peptide corresponding to residues surrounding Y39 of human histone H2A.
Theoretical MW (kDa)
Calculated MW: 14 kD
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
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Gene Info — HIST1H2AE
Entrez GeneID
3012Protein Accession#
P04908Gene Name
HIST1H2AE
Gene Alias
H2A.1, H2A.2, H2A/a, H2AFA
Gene Description
histone cluster 1, H2ae
Omim ID
602786Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq
Other Designations
H2A histone family, member A|histone 1, H2ae|histone H2AE
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