IRAK4 recombinant monoclonal antibody, clone 10H4
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: THP-1 whole cell lysate; Lane 2: U251 whole cell lysate.
Flow Cytometry
Overlay histogram showing Jurkat cells stained with IRAK4 recombinant monoclonal antibody, clone 10H4 (red line) at 1:50.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human IRAK4.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human IRAK4.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry (1:20-1:200)
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: THP-1 whole cell lysate; Lane 2: U251 whole cell lysate.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay histogram showing Jurkat cells stained with IRAK4 recombinant monoclonal antibody, clone 10H4 (red line) at 1:50. -
Gene Info — IRAK4
Entrez GeneID
51135Protein Accession#
Q9NWZ3Gene Name
IRAK4
Gene Alias
IPD1, NY-REN-64, REN64
Gene Description
interleukin-1 receptor-associated kinase 4
Gene Ontology
HyperlinkGene Summary
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeq
Other Designations
IRAK-4 mutated form 1|interleukin-1 receptor associated kinase 4
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Interactome
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Pathway
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Disease
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