GPX4 recombinant monoclonal antibody, clone 9D4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human GPX4.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human GPX4.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of GPX4 recombinant monoclonal antibody, clone 9D4 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GPX4
Entrez GeneID
2879Protein Accession#
P36969Gene Name
GPX4
Gene Alias
MCSP, PHGPx, snGPx, snPHGPx
Gene Description
glutathione peroxidase 4 (phospholipid hydroperoxidase)
Omim ID
138322Gene Ontology
HyperlinkGene Summary
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq
Other Designations
glutathione peroxidase 4|phospholipid hydroperoxidase|phospholipid hydroperoxide glutathione peroxidase, mitochondrial|sperm nucleus glutathione peroxidase
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Interactome
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Disease
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