GZMB recombinant monoclonal antibody, clone 6A1
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunohistochemistry
Immunohistochemistry image of GZMB recombinant monoclonal antibody, clone 6A1 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system.
Immunofluorescence
Immunofluorescence staining of Hela Cells with GZMB recombinant monoclonal antibody, clone 6A1 at 1:50, counter-stained with DAPI.
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human GZMB.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human GZMB.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
Immunofluorescence(1:20-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Immunohistochemistry
Immunohistochemistry image of GZMB recombinant monoclonal antibody, clone 6A1 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system.Immunofluorescence
Immunofluorescence staining of Hela Cells with GZMB recombinant monoclonal antibody, clone 6A1 at 1:50, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — GZMB
Entrez GeneID
3002Protein Accession#
P10144Gene Name
GZMB
Gene Alias
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Gene Description
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Omim ID
123910Gene Ontology
HyperlinkGene Summary
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq
Other Designations
T-cell serine protease 1-3E|cathepsin G-like 1|cytotoxic serine protease B|fragmentin 2|granzyme B
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com