IL4 recombinant monoclonal antibody, clone 5D8
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human IL4.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human IL4.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20 °C or -80 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of IL4 recombinant monoclonal antibody, clone 5D8 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL4
Entrez GeneID
3565Protein Accession#
P05112Gene Name
IL4
Gene Alias
BCGF-1, BCGF1, BSF1, IL-4, MGC79402
Gene Description
interleukin 4
Omim ID
147780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
B cell growth factor 1|B_cell stimulatory factor 1|lymphocyte stimulatory factor 1
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