TNF recombinant monoclonal antibody, clone RMTNFA-1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against recombinant human TNF-alpha protein.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to recombinant human TNF-alpha protein
Reactivity
Human
Form
Liquid
Conjugation
Unconjugated
Purification
Protein A affinity chromatography
Concentration
0.2 mg/mL
Isotype
IgG
Recommend Usage
Immunofluorescence (5-10 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(5-10 ug/mL for 30 min at RT)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage Instruction
Store at 2~8°C.
Aliquot to avoid repeated freezing and thawing.Note
Optimal dilutions for each application to be determined by the researcher
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of human histiocytoma with anti-TNF alpha recombinant monoclonal antibody, clone RMTNFA-1 (Cat # RAB03832).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of human pancreas with anti-TNF alpha recombinant monoclonal antibody, clone RMTNFA-1 (Cat # RAB03832).Immunofluorescence
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Gene Info — TNF
Entrez GeneID
7124Protein Accession#
P01375Gene Name
TNF
Gene Alias
DIF, TNF-alpha, TNFA, TNFSF2
Gene Description
tumor necrosis factor (TNF superfamily, member 2)
Gene Ontology
HyperlinkGene Summary
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq
Other Designations
APC1 protein|OTTHUMP00000029281|OTTHUMP00000037669|TNF superfamily, member 2|TNF, macrophage-derived|TNF, monocyte-derived|cachectin|tumor necrosis factor alpha
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