RAD23B recombinant monoclonal antibody, clone SAIC-28A-29
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide corresponding to human UV excision repair protein RAD23 homolog B, conjugated to KLH.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human UV excision repair protein RAD23 homolog B, conjugated to KLH
Sequence
ILNDDTALK
Reactivity
Human
Form
Liquid
Conjugation
Unconjugated
Concentration
batch dependent
Isotype
IgG
Recommend Usage
Flow cytometry
Immunofluorescence
ImmunoMRM
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for 3 months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
For research use only.
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Applications
Western Blot
Immunofluorescence
Immunofluorescence analysis of RAD23B (green) in HeLa cells using human anti-RAD23B recombinant monoclonal antibody, clone SAIC-28A-29 (Cat # RAB03773), and DAPI(blue).Flow Cytometry
Flow-cytometry analysis of RAD23B in HeLa cells using human anti-RAD23B recombinant monoclonal antibody, clone SAIC-28A-29 (Cat # RAB03773).Immuno-MRM (multiple reaction monitoring)
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Gene Info — RAD23B
Entrez GeneID
5887Protein Accession#
P54727Gene Name
RAD23B
Gene Alias
HHR23B, HR23B, P58
Gene Description
RAD23 homolog B (S. cerevisiae)
Omim ID
600062Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq
Other Designations
OTTHUMP00000021857|RAD23, yeast homolog of, B|UV excision repair protein RAD23 homolog B|XP-C repair complementing complex 58 kDa|XP-C repair complementing protein
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Interactome
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Pathway
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Disease
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