FGA recombinant monoclonal antibody, clone 3B6
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More Files
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Enzyme-linked Immunoabsorbent Assay
ELISA analysis of FGA recombinant monoclonal antibody, clone 3B6 (Cat # RAB03410).
Binding curve of the antibody RAB03410 (blue line) to an ELISA plate coated with D-dimer protein (Bio-Rad 4440-0256) at a concentration of 5 ug/mL. A 3-fold serial dilution from 10,000 ng/mL was performed using RAB03410. For signal detection a 1:4,000 dilution of HRP-lnti-r antibody was used. Ri-Fluorescein [4-4-20 (enhanced)] antibody was used as a control (orange curve).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FGA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against human cross-linked D-Dimer.
Reactivity
Human
Form
Liquid
Isotype
IgG kappa
Recommend Usage
ELISA
LFIA
Latex and RBC Agglutination
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of FGA recombinant monoclonal antibody, clone 3B6 (Cat # RAB03410).
Binding curve of the antibody RAB03410 (blue line) to an ELISA plate coated with D-dimer protein (Bio-Rad 4440-0256) at a concentration of 5 ug/mL. A 3-fold serial dilution from 10,000 ng/mL was performed using RAB03410. For signal detection a 1:4,000 dilution of HRP-lnti-r antibody was used. Ri-Fluorescein [4-4-20 (enhanced)] antibody was used as a control (orange curve).Lateral-Flow Immunochromatographic Assay
Agglutination
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Gene Info — FGA
Entrez GeneID
2243Gene Name
FGA
Gene Alias
Fib2, MGC119422, MGC119423, MGC119425
Gene Description
fibrinogen alpha chain
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq
Other Designations
fibrinogen, A alpha polypeptide|fibrinogen, alpha chain, isoform alpha preproprotein|fibrinogen, alpha polypeptide
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Interactome
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Pathway
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Disease
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