Products

Western Blot

Western blot analysis of human liver (35ug protein in RIPA buffer) lysates with ACKR1 recombinant monoclonal antibody, clone 2C3 (Cat # RAB03402). A primary incubation of 1h was used and protein was detected by chemiluminescence.

Immunofluorescence

Immunofluorescent staining of HepG2 cells with ACKR1 recombinant monoclonal antibody, clone 2C3 (Cat # RAB03402).
Immunofluorescence analysis of paraformaldehyde HepG2 cells fixed on Shi-fix™ coverslips, permeabilized with 0.15% Triton stained with the chimeric r version of RAB03402 at 10 ug/mL for 1h followed by Alexa Fluor® 488 secondary antibody (1 ug/mL), showing cytoplasmic staining likely of endosomes and some membrane staining. The nuclear stain is DAPI (blue). The isotype control was stained with an anti-Fluorescein antibody.

Enzyme-linked Immunoabsorbent Assay

Blocking

Flow Cytometry

Entrez GeneID

2532

Gene Name

DARC

Gene Alias

CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1

Gene Description

Duffy blood group, chemokine receptor

Omim ID

110700 611162

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Other Designations

Duffy antigen/chemokine receptor|Duffy blood group antigen|Fy glycoprotein|OTTHUMP00000035293|OTTHUMP00000060081|glycoprotein D