Products

Western Blot

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunocytochemistry

Immunofluorescence

Immunofluorescent staining of Daudi cells with CD37 recombinant monoclonal antibody, clone MB-1 (Cat # RAB03240).
OX-126 Immunofluorescence analysis of paraformaldehyde fixed Daudi cells stained with the chimeric mouse IgG version of RAB03240 at 10 ug/ml followed by Alexa Fluor® 488 secondary antibody (2 ug/ml)- showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right- top-bottom RAB03240- DAPI- merged channels and an isotype control. The isotype control was stained with anti-unknown antibody (.1) followed by Alexa Fluor® 488 secondary antibody.

Flow Cytometry

Flow cytometric analysis of Daudi cells with CD37 recombinant monoclonal antibody, clone MB-1 (Cat # RAB03240).
Daudi cells were stained with anti-unknown specificity antibody (.1; isotype control- black line) or the mouse IgG1 version of RAB03240 (blue line) at a dilution of 1:100 for 1h at RT. After washing- the bound antibody was detected using a goat anti-mouse IgG AlexaFluor® 488 antibody at a dilution of 1:1000 and cells analyzed using a FACSCanto flow-cytometer.

Entrez GeneID

951

Gene Name

CD37

Gene Alias

GP52-40, MGC120234, TSPAN26

Gene Description

CD37 molecule

Omim ID

151523

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Other Designations

CD37 antigen|cell differentiation antigen 37|leukocyte surface antigen CD37|tetraspanin-26