JAK3 recombinant monoclonal antibody, clone JAK3Y980981-E10 (PE)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of Ramos cells untreated (red) or treated with pervanadate (green) using Phospho-Jak3 (Tyr980/981) (E10) Rabbit mAb (PE Conjugate) JAK3Y980981-E10, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (PE Conjugate) for cells untreated (black) or treated with pervanadate (blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human JAK3.
Antibody Species
Rabbit
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr980/981 of human Jak3
Reactivity
Human
Form
Liquid
Purification
Protein A+G
Isotype
Rabbit IgG1k
Conjugation Note
PE
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
1X PBS, 0.09% Sodium azide, 0.2% BSA
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of Ramos cells untreated (red) or treated with pervanadate (green) using Phospho-Jak3 (Tyr980/981) (E10) Rabbit mAb (PE Conjugate) JAK3Y980981-E10, or concentration-matched Rabbit (G9) mAb IgG Isotype Control (PE Conjugate) for cells untreated (black) or treated with pervanadate (blue). -
Gene Info — JAK3
Entrez GeneID
3718Protein Accession#
P52333Gene Name
JAK3
Gene Alias
JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Gene Description
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
Omim ID
600173Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq
Other Designations
Janus kinase 3|leukocyte Janus kinase|tyrosine-protein kinase JAK3
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Interactome
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Pathway
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Disease
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