ASK1 recombinant monoclonal antibody

Catalog # RAB02472

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Price

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Quantity

Size:100 uL
Price: USD $ 531.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of Hela (A) whole cell lysates with ASK1 recombinant monoclonal antibody (Cat # RAB02472).

  • Specification

    Product Description

    Rabbit recombinant monoclonal antibody raised against human ASK1.Recombinant Antibody,Recombinant Antibodies,Recombinant Monoclonal Antibody,RecomAb,Recombinant Ab,Recombinant Monoclonal Antibodies,Recombinant Abs

    Antibody Species

    Rabbit

    Immunogen

    Original antibody is raised against a synthetic peptide of human ASK1.

    Theoretical MW (kDa)

    155

    Reactivity

    Human

    Specificity

    Recognizes endogenous levels of ASK1 protein.

    Form

    Liquid

    Purification

    Immunogen affinity chromatography

    Isotype

    IgG

    Recommend Usage

    Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 50mM Tris-Glycine, pH 7.4 (0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA)

    Storage Instruction

    Store at 4°C short term.
    Aliquot and store at -20°C long term.
    Avoid freeze-thaw cycles.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of Hela (A) whole cell lysates with ASK1 recombinant monoclonal antibody (Cat # RAB02472).
  • Gene Info — MAP3K5

    Entrez GeneID

    4217

    Protein Accession#

    Q99683

    Gene Name

    MAP3K5

    Gene Alias

    ASK1, MAPKKK5, MEKK5

    Gene Description

    mitogen-activated protein kinase kinase kinase 5

    Omim ID

    602448

    Gene Ontology

    Hyperlink

    Gene Summary

    Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. [provided by RefSeq

    Other Designations

    MAP/ERK kinase kinase 5|MAPK/ERK kinase kinase 5|OTTHUMP00000017275|apoptosis signal regulating kinase

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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