AT1 recombinant monoclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against recombinant AT1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide of human Angiotensin II Type 1 Receptor.
Theoretical MW (kDa)
41
Reactivity
Human
Specificity
Recognizes endogenous levels of AT1 protein.
Form
Liquid
Purification
Immunogen affinity chromatography
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
Storage Buffer
In 50mM Tris-Glycine, pH 7.4 (0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 (A) whole cell lysates with AT1 recombinant monoclonal antibody (Cat # RAB02412). -
Gene Info — AGTR1
Entrez GeneID
185Protein Accession#
P30556Gene Name
AGTR1
Gene Alias
AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Gene Description
angiotensin II receptor, type 1
Gene Ontology
HyperlinkGene Summary
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq
Other Designations
angiotensin receptor 1|angiotensin receptor 1B|type-1B angiotensin II receptor
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com