FH recombinant monoclonal antibody, clone R08-3F2
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: CHO-K1, Lane 2: C6 and Lane 3: Jurkat lysates with FH recombinant monoclonal antibody, clone R08-3F2 (Cat # RAB02281).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FH.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human FH.
Theoretical MW (kDa)
Calculated MW: 55 kD
Reactivity
Hamster, Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: CHO-K1, Lane 2: C6 and Lane 3: Jurkat lysates with FH recombinant monoclonal antibody, clone R08-3F2 (Cat # RAB02281).Immunofluorescence
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Gene Info — FH
Entrez GeneID
2271Protein Accession#
P07954Gene Name
FH
Gene Alias
HLRCC, LRCC, MCL, MCUL1
Gene Description
fumarate hydratase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq
Other Designations
OTTHUMP00000037573|fumarase|multiple hereditary cutaneous leiomyomata
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Interactome
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Pathway
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Disease
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