FBL recombinant monoclonal antibody, clone R09-7E5
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: K562, Lane 2: C6 and Lane 3: 3T3 lysates with FBL recombinant monoclonal antibody, clone R09-7E5 (Cat # RAB02279).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FBL.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human FBL.
Theoretical MW (kDa)
Calculated MW: 34 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: K562, Lane 2: C6 and Lane 3: 3T3 lysates with FBL recombinant monoclonal antibody, clone R09-7E5 (Cat # RAB02279).Immunoprecipitation
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Gene Info — FBL
Entrez GeneID
2091Protein Accession#
P22087Gene Name
FBL
Gene Alias
FIB, FLRN, RNU3IP1
Gene Description
fibrillarin
Omim ID
134795Gene Ontology
HyperlinkGene Summary
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq
Other Designations
34-kD nucleolar scleroderma antigen|RNA, U3 small nucleolar interacting protein 1
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Interactome
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Disease
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