IKBKG monoclonal antibody, clone R06-5G4
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: K562 and Lane 2: Hela lysates with IKBKG recombinant monoclonal antibody, clone R06-5G4 (Cat # RAB02176).
Immunocytochemistry
Immunocytochemical staining of Hela with IKBKG recombinant monoclonal antibody, clone R06-5G4 (Cat # RAB02176). (A) IKBKG (green) and (B) DAPI (blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human IKBKG.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human IKBKG.
Theoretical MW (kDa)
Calculated MW: 48 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence(1:50-1:200)
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: K562 and Lane 2: Hela lysates with IKBKG recombinant monoclonal antibody, clone R06-5G4 (Cat # RAB02176).Immunocytochemistry
Immunocytochemical staining of Hela with IKBKG recombinant monoclonal antibody, clone R06-5G4 (Cat # RAB02176). (A) IKBKG (green) and (B) DAPI (blue).Immunofluorescence
Immunoprecipitation
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Gene Info — IKBKG
Entrez GeneID
8517Protein Accession#
Q9Y6K9Gene Name
IKBKG
Gene Alias
AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO
Gene Description
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Gene Ontology
HyperlinkGene Summary
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [supplied by RefSeq
Other Designations
NFkappaB essential modulator|OTTHUMP00000026027|OTTHUMP00000026028|OTTHUMP00000026029|incontinentia pigmenti
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Interactome
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Pathway
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Disease
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