LUM recombinant monoclonal antibody, clone R02-7F6
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human LUM.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human LUM.
Theoretical MW (kDa)
Calculated MW: 38 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence(1:50-1:200)
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: K562, Lane 2: C6 and Lane 3: Hela lysates with LUM recombinant monoclonal antibody, clone R02-7F6 (Cat # RAB02125).Immunohistochemistry
Immunocytochemistry
Immunocytochemical staining of Hela with LUM recombinant monoclonal antibody, clone R02-7F6 (Cat # RAB02125). (A) LUM (green) and (B) DAPI (blue).Immunofluorescence
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Gene Info — LUM
Entrez GeneID
4060Protein Accession#
P51884Gene Name
LUM
Gene Alias
LDC, SLRR2D
Gene Description
lumican
Omim ID
600616Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq
Other Designations
lumican proteoglycan
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Interactome
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Disease
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