CHRM2 recombinant monoclonal antibody, clone R01-9B9
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: K562, Lane 2: C6 and Lane 3: Hela lysates with CHRM2 recombinant monoclonal antibody, clone R01-9B9 (Cat # RAB02089).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CHRM2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human CHRM2.
Theoretical MW (kDa)
Calculated MW: 52 kD
Reactivity
Human, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: K562, Lane 2: C6 and Lane 3: Hela lysates with CHRM2 recombinant monoclonal antibody, clone R01-9B9 (Cat # RAB02089).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — CHRM2
Entrez GeneID
1129Protein Accession#
P08172Gene Name
CHRM2
Gene Alias
FLJ43243, HM2, MGC120006, MGC120007
Gene Description
cholinergic receptor, muscarinic 2
Omim ID
118493Gene Ontology
HyperlinkGene Summary
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
Other Designations
7TM receptor|cholinergic receptor, muscarinic 2, isoform a|muscarinic M2 receptor|muscarinic acetylcholine receptor M2
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Interactome
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Pathway
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Disease
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