PIK3CG recombinant monoclonal antibody, clone R09-5C8
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PIK3CG.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human PIK3CG.
Theoretical MW (kDa)
Calculated MW: 126 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of K562 lysates with PIK3CG recombinant monoclonal antibody, clone R09-5C8 (Cat # RAB01999).Immunoprecipitation
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Gene Info — PIK3CG
Entrez GeneID
5294Protein Accession#
P48736Gene Name
PIK3CG
Gene Alias
PI3CG, PI3K, PI3Kgamma, PIK3
Gene Description
phosphoinositide-3-kinase, catalytic, gamma polypeptide
Omim ID
601232Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq
Other Designations
1-phosphatidylinositol 3-kinase|PI3-kinase|PTDINS-3-kinase|p110-gamma|phosphatidylinositol 3 kinase gamma, p110 gamma|phosphatidylinositol 3-kinase catalytic 110-kD gamma|phosphatidylinositol 3-kinase, catalytic, gamma polypeptide|phosphoinositide-3-kinas
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Interactome
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Disease
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