RAB7A recombinant monoclonal antibody, clone R01-3K3
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human RAB7A.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human RAB7A.
Theoretical MW (kDa)
Calculated MW: 23 kD
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of 3T3 lysates with RAB7A recombinant monoclonal antibody, clone R01-3K3 (Cat # RAB01965).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin/PFA-fixed paraffin-embedded sections) of human lung cancer with RAB7A recombinant monoclonal antibody, clone R01-3K3 (Cat # RAB01965).
High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. -
Gene Info — RAB7A
Entrez GeneID
7879Protein Accession#
P51149Gene Name
RAB7A
Gene Alias
FLJ20819, PRO2706, RAB7
Gene Description
RAB7A, member RAS oncogene family
Gene Ontology
HyperlinkGene Summary
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq
Other Designations
RAB7, member RAS oncogene family|Ras-associated protein RAB7
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Interactome
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Disease
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