SIRT3 recombinant monoclonal antibody, clone R03-1F5
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More Files
- More Functions
Western Blot
Western blot analysis of Lane1: Jurkat and Lane2: Hela lysates with SIRT3 recombinant monoclonal antibody, clone R03-1F5 (Cat # RAB01911).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SIRT3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human SIRT3.
Theoretical MW (kDa)
Calculated MW: 44 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane1: Jurkat and Lane2: Hela lysates with SIRT3 recombinant monoclonal antibody, clone R03-1F5 (Cat # RAB01911).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — SIRT3
Entrez GeneID
23410Protein Accession#
Q9NTG7Gene Name
SIRT3
Gene Alias
SIR2L3
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
Omim ID
604481Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq
Other Designations
mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase|silent mating type information regulation 2, S.cerevisiae, homolog 3|sir2-like 3|sirtuin 3|sirtuin type 3
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Interactome
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Disease
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