TMEM43 recombinant monoclonal antibody, clone R07-9D4
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More Files
- More Functions
Western Blot
Western blot analysis of Lane1: K562 and Lane2: C6 lysates with TMEM43 recombinant monoclonal antibody, clone R07-9D4 (Cat # RAB01861).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TMEM43.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human TMEM43.
Theoretical MW (kDa)
Calculated MW: 45 kD
Reactivity
Human, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane1: K562 and Lane2: C6 lysates with TMEM43 recombinant monoclonal antibody, clone R07-9D4 (Cat # RAB01861).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — TMEM43
Entrez GeneID
79188Protein Accession#
Q9BTV4Gene Name
TMEM43
Gene Alias
ARVC5, ARVD5, DKFZp586G1919, LUMA, MGC3222
Gene Description
transmembrane protein 43
Gene Ontology
HyperlinkGene Summary
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. [provided by RefSeq
Other Designations
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Interactome
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Disease
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