YWHAB recombinant monoclonal antibody, clone R08-4A7
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: rat brain and Lane 2: rat lung lysates with YWHAB recombinant monoclonal antibody, clone R08-4A7 (Cat # RAB01771).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human YWHAB.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide of human YWHAB.
Theoretical MW (kDa)
Calculated MW: 28 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1/50-1/100)
Immunoprecipitation (1/20)
Western Blot (1/500-1/1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: rat brain and Lane 2: rat lung lysates with YWHAB recombinant monoclonal antibody, clone R08-4A7 (Cat # RAB01771).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — YWHAB
Entrez GeneID
7529Protein Accession#
P31946Gene Name
YWHAB
Gene Alias
GW128, HS1, KCIP-1
Gene Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Omim ID
601289Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq
Other Designations
14-3-3 protein beta/alpha|OTTHUMP00000031075|OTTHUMP00000031076|brain protein 14-3-3, beta isoform|protein 1054|protein kinase C inhibitor protein-1
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Interactome
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Pathway
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Disease
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