CENPA recombinant monoclonal antibody, clone R04-9A5
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against synthetic peptide of human CENPA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human CENPA
Theoretical MW (kDa)
Calculated MW: 16 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1,000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of CENPA in K562, Hela lysates using human CENPA recombinant monoclonal antibody, clone R04-9A5 (Cat # RAB01727). -
Gene Info — CENPA
Entrez GeneID
1058Protein Accession#
P49450Gene Name
CENPA
Gene Alias
CENP-A
Gene Description
centromere protein A
Omim ID
117139Gene Ontology
HyperlinkGene Summary
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000122589|centromere protein A, 17kDa
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